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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae1599a9238bbbe0e6539bee6a0f30db45939d2f256954bf71f528fefec8d4b1' 
  AND token = 'jNzPXwhDKVDFDc4SZ5k7ePRbE6h14fz7jhW4zGCTvzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}