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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2860dbbc1dacadea8c782dd8e6d05ab0f3748e1a964a63f051e2494feec46b2' 
  AND token = 'rVHdn02d7FX4vAwpVTw6OKg6BaO8tS8mHG2fLcnpRDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}