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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2e9430b4b9c03d9566b84e3556e0d9c196de3ba14feff88f1334224ae4600f6' 
  AND token = 'H+kAH75j/uYJDK3U7vDMesmqWx8AJWjexpe7csqPaic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}