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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a25248635dd71909a048035b1bbd9248920df20fd829d3bfa9c53e4f1f7042b7' 
  AND token = '2eisVcUOLi7k45gmNbH8KOkDjhfFhidVD0sEngSrqoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}