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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5b180db65a08ad2a365cbddb1514202c3543ecaedac72d05d8f469fce63db5a' 
  AND token = '+ne4A9lpUj2qUk9VuCQFU+aZDRJxt5XBkXc99Fikoeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}