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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e131efd5da1d15c6736bceed4a83277727f407e217ce717301ddc0a0c05d6c38' 
  AND token = '9TB/fY+SKZ57M/a4gF4/YgTtXQJHTgOTCwH0TCRJlU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}