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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c84ada8ecc7b34e10f875e11a6be408aed8c580b22c88f3108db1fb6ccfabbb' 
  AND token = '1hMpJBz5K/v1+DC5zOPmiLL0XUWsoi2wjZ+87aijbMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}