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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44cfd349e35fe189d5234a8be675543844831ce8db6c0e325f3e709bef571b3c' 
  AND token = '/F+Ytx/j+cB5gzwZo2bokFqtiCDD1CSikPAHKeP2now=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}