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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80d237b820847c486bc94b1dc4691d2e03537557c9876f95a4a201e36652cc9c' 
  AND token = 'CFs+KKFpTGxXFCvi+tTOYUuUqFH2Qr9aENY2SzfnT0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}