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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5958f3b8f8bd927b7ce8f68f14c74231edfffaf5dc81f1dbe04d6af417ffb62d' 
  AND token = 'DM5YtqivGz5LLcLiVrWka4iA+0yzY2b+ZBUAsBt3buU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}