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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1dc2ce0776f4bbdafd9ec47934eac0a00f90a4d99d750a1110b765816222f2a' 
  AND token = 'NNRKarGfzAP2E6020h9278imcmzLM5tJ1T5xPh7Unew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}