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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3921d1eff53bf5759d7cbc36891d2ad2932eb534bbb40e4512f414589350b565' 
  AND token = 'u8fUMDMciCEqfIFjx6+Kf9lSZQQPA6GrZGob8c2tNN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}