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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dc45d8c71f515def523f6b1fb422ebe9ef925965223b4a2b7bad77b69985794' 
  AND token = '1FxwnrTUyFZccDgc9oF2+1uQq+lxo/l5SR/mc2THry0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}