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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd49e18a2c8c0ad64880aad9edf3d28a3f63e9e4ddac9761354ff46bb2c40903e' 
  AND token = 'txCDrBnz1Cuiaa0iVbMB9AYQpTGQD+eeK6dP/BIC6Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}