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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a27c791dd0f6ce7792408709ae4c98e68b3515e874c06100e7e3b5a79b3cc8b' 
  AND token = '7adLyjS2B2Ox1z2EAR2vkYWVIU1lEx9yCMbrEA5OsfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}