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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b59a496810e998186ca77da2359a1e80303707bf76ecd021e0b1d0a609725838' 
  AND token = 'n/yPLsIkdCSvhifhv0dhx6tZJawNT2Vi7ctgCezrWiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}