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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce13b53f1033564f80cdaea6963ed50997e2809b5d2d4a46266ce022837c0188' 
  AND token = 'woAJ7SK5L0bF+US47zesihudXMiwC8NcmC7iDJyTccs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}