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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '323d9ad20cc65a18c4ccc4f87e99a6db26e2139222c76e482e77bc40c928e00a' 
  AND token = 'KOigD1YUanK0tyj+Vhl2sSpKAXT2cx4bWC5KzGuXm2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}