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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f9d0c0a145b7dbd6c410e484ae595f706c9c93af7c444c562932104941acf24' 
  AND token = 'IFXwYRi3V5VGICv31yeGl+DNuBXwTCtwit+OvTayIxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}