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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5d544a6c5ce32ecc0a3dbda1225acc2b693f626d2f6f5c456ac1d443539e7d' 
  AND token = 'R/MDDeIcrVdtEsa3tAgfT4Ae7ka8EPfgxHYJErQcqOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}