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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1044e144d06d80d520d2b2c58f05564c927df62b525e544640326887d9f1fa9a' 
  AND token = 'GuOazPB7XLtCnTu2Xav1O8jJO51Bd3MAKo85H81AuQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}