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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9635093dbdc929544c669118d042182c9e82b6c3ad452c2d0d0a573ee2e41896' 
  AND token = '34UNjMa8wKNBp0otEeO4wrp2e4dqbRsPqgtUTrdOKz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}