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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41a2cd85eae094b9336653292a96b55c480991621de9070b8dab60214ae530af' 
  AND token = 'nDVTfPrFCnAkpnNC4++JwAV2yf+dxxLzDo6NjiDWxrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}