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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04f4de72dea8625606dfefdd47940404f9999a448a8151ff53993b08834f367a' 
  AND token = 'EzA6+a5E9Z3i/kbBmutjJ8LFTLVyNiq6RmRPlawupw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}