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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e318122f0098644fe4b6556333b497823bdceec017f577995ac6aaa7a35b782' 
  AND token = 'TZjf0KS/FvevGbvTKE9MMLYRu1hL5uzE3vFSeJW5xxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}