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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86271a261bd9cf590be3bfb8fef7c6b53533d9634101df88a771291125d29ef5' 
  AND token = 'W8F6F8JUaIFkvOxOs59n6Sftg9y00D/ZCsFep1Lh+u4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}