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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad2114812e0b2fd731a741a338c1e12bd1b64f956b11de8a8985c2ca388db45a' 
  AND token = 'Dy0DGHX/BsWzBEXA3a9DGhC6OrTAN6rPpILRORoON4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}