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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e52a4376d579072a350cc353b514ad50f39df850477bf957ac01c826cb99717' 
  AND token = 'l6i6b8OFY3ZAC9k8QkDDTCiBHMVYdNLqlyMdyWhoXEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}