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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8fda0c33fe6278e034d9acc3ba2fffe86e326a535027e5390dd19c0ed43bed6' 
  AND token = 'arriaNI95R+N1TSmmt+LKHPxAR4yM55e2w0ITzV2R6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}