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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '784372f7e123b80586e94929a2e4895cbd5baf1ed2b3c4244989be5e689e3eb9' 
  AND token = 'bsf4tz6KVoBPJTsgR8zUu1gnHMnqJknFxtOJZM8TT18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}