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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5ee177e1988e74b13e9bc3cc8d5ec3944060ba50a63e273e2955990c77a043c' 
  AND token = 'VO2x7cb3N6E6NS8XzqxdfejP57UuAqGgcWLlwCCQVq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}