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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433b147493033c178011b938e44d849fdfa83964373bb0d5223fbd0cb3a1d335' 
  AND token = 'yq5GblHSAEz6TGCB7RCHtocUCrg9hzMof31rcz6IMcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}