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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a04b8242644642e5c1001e54dfdac96524ebd7ded5c77bbe14925ba2000223c' 
  AND token = '2G+4KtJpU5G8EIb9vPx4zRV5B0qQ7F+4FU2CrKPjvr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}