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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac77d42ff04c05596848079d7a6d620eec03b33918d168359b9516a8c145584' 
  AND token = 'KEQqr8SIyRzA4+Xz+EJ613G/2IwI/r6uq5pcEQC4/wA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}