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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b187c9d435f7a88b22286998ab794f86990b9f3cc1e5423170b4bcb9627d029' 
  AND token = 'mlV2bfqYj11CE4Zbj99x8PapqEHgePLJYE3inPpTZ0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}