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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61cd0b60e7222c66f5f573f335e5885e48780efec88e7719b6516ca7be0c4210' 
  AND token = '/K0bXI7uT/N/KVAE9dm/X3v8q8G5+xhptxg4jMrFsSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}