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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f39b814c1629b502a9d5a997b0871d266d46c2d0233902337d0dee2cbdc7823' 
  AND token = '648Qx5QnJfayW5f6j4PmOQRh3eSjGVczjUe18AgycMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}