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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a8978b2d205d512fb79787b1bd6b762cd216b6ace2a34a2f27cf75e64ad9267' 
  AND token = 'hK6aY/phkMdQAZnJ8kSm8uv7AfwH5K9s+xx+MyiAxqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}