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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9607b0fe9c401695839b012623fea0369014281fb3a1be1f678a659a79a1011c' 
  AND token = 'eDHzN+zXqQQAem+k6Iqf3xNzq3UMHFGAzVxRIfYW7cU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}