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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16a3c1b3f4bab4b320c667e069c35b90629f4d617d8355d008cfe1a18d75a8f6' 
  AND token = 'z+gG6cU0v3SvKwn4TWr6NPc1YfqURWeSf9tw5Atjeto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}