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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6b75652b4f028f4b49d673bd2c221de45a29622491c768e6922e928ab873cfc' 
  AND token = 'pD/RV5wr9ie4aX8W9OYWkV64naAiL7gdlFObomGMh0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}