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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ac0b9b2eb6f3b479795c257b4ff5d7bf9c766975bba0551c89b77454874edb2' 
  AND token = '2bNWAPaVju34EenoZeON/uqOUpToJWov/fwEiTHs338=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}