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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '173dec2e3bb528f5ff9cd71c56fb2fff0d25ab4ceb9263e0c1918b6dc4bd2121' 
  AND token = 'fy+snkYoBxUOFPt8EiL74j4ZA/a3MdYbvkqybu47fh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}