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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1449d685630fd2042f601e25e1f930bf2135bcdb9add3184e975bf6cd42d61af' 
  AND token = 'Y2nzbmcCICA/Lp1u2b0ZsFa+HqXwB7puiVWYtAAa7us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}