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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bc4e1f6771ef5d287b683753c005a7759805c4f88f2d1863823d2eaf6ba96fd' 
  AND token = 'S2wyxXgHBELyVz5FjCehmjgFjLnw0CSVpNowF/02hyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}