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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cb545e41ed718d2784ee40c963d65ce4e8747a1ffa68206f6a5c5b153ced3d8' 
  AND token = '5iRQP3J/ZWVNoTcAvTDay/4cWeXdowzq/ApYdkVGoO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}