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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ec41f681b4728b9a22bb05a84fb423fece81b83dea4a136b6b7a507b11a37c5' 
  AND token = 'nA7eEBqS8nCSNdnNMxIKmxcU0s6SynOzW23UNiVrfbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}