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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50c6f45e0b0d9e47e4879e267bb1789f412f4d4d45151d9fd3e50f06df22478e' 
  AND token = 'PIWGAGtqIp31Ga4T6O6RlWzQJ943i2CuR51SnSIZrY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}