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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4161f6df42097ff89e6c4b3dd55a828f84208350efd3d03eeb17ac664250b67c' 
  AND token = '5dn0TJ8I4CZrdvy29xIG+lWLXG085eZfnfMQzDuUYyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}