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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5ad87e12c271224124de4ebc6b5395809cbe3733646ed7efa1fc0830accde1b' 
  AND token = 'ra2Ncgd4QiVWZe4YmEXOtE9hXixZCrWcJ+YTn3SrCg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}